Correlation between the anatomical and functional human subthalamic nucleus

被引：15

作者：

Nowinski, Wieslaw L.

Thirunavuukarasuu, A.

Liu, Jimin

Benabid, Alim Louis

机构：

[1] Biomed Imaging Lab, Agcy Sci Technol & Res, Singapore 138671, Singapore

[2] Grenoble Univ Hosp, Grenoble, France

来源：

STEREOTACTIC AND FUNCTIONAL NEUROSURGERY | 2007年 / 85卷 / 2-3期

关键词：

subthalamic nucleus; brain atlas; function; anatomy;

D O I：

10.1159/000097924

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

This work addresses the spatial correlation between the anatomical and functional human subthalamic nucleus (STN). The anatomical STN (A-STN), derived from the Schalten-brand-Wahren brain atlas, is histology based. The functional STN (F-STN) is probabilistic, constructed from neuroelectrophysiological and neuroimaging data of 184 Parkinson's disease patients. The A-STN and F-STN are placed in the same space and compared in terms of mutual relative overlapping of anatomy with function. The F-STN and A-STN correlate well for medium and high probabilities of the F-STN. For probability p >= 0.3, > 95% of F-STN is inside the A-STN, and for p >= 0.5, the complete F-STN is inside the A-STN for each left and right STN. Therefore, the F-STN for p = 0.5 can potentially be used for identification of the STN in neuroimages. Copyright (c) 2007 S. Karger AG, Basel.

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页码：88 / 93

页数：6

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