Central and peripheral clocks in cardiovascular and metabolic function

被引：40

作者：

Curtis, Anne M. ^{[1
]}

Fitzgerald, Garret A. ^{[1
]}

机构：

[1] Univ Penn, Sch Med, Inst Translat Med & Therapeut, Philadelphia, PA 19104 USA

来源：

ANNALS OF MEDICINE | 2006年 / 38卷 / 08期

关键词：

cardiovascular and metabolic function; cardiovascular disease; central and peripheral clocks; circadian rhythms; chronotherapy; environmental stress;

D O I：

10.1080/07853890600995010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The molecular circadian clock entrains biological rhythms to a 24-hour schedule. Aspects of cardiovascular physiology and, indeed, the incidence of myocardial infarction and stroke are also subject to diurnal variation. The use of rodent models of disrupted clock function has begun to elucidate the role of the molecular clock in the pathophysiology of cardiovascular and metabolic disease.

引用

页码：552 / 559

页数：8

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