Dithlolato-bridged dinuclear iron-nickel complexes [Fe(CO)2(CN)2(μ-SCH2CH2CH2S)Ni(S2CNR2)]- -: Modeling the active site of [NiFe] hydrogenase

被引：138

作者：

Li, ZL

Ohki, Y

Tatsumi, K ^{[1
]}

机构：

[1] Nagoya Univ, Res Ctr Mat Sci, Chikusa Ku, Nagoya, Aichi 4648602, Japan

[2] Nagoya Univ, Grad Sch Sci, Dept Chem, Chikusa Ku, Nagoya, Aichi 4648602, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 25期

关键词：

D O I：

10.1021/ja051590+

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[NiFe] hydrogenase, the enzyme of which catalyzes the reversible oxidation of molecular hydrogen to protons and electrons, contains a unique heterodinuclear thiolate-bridged Ni-Fe complex in which the iron center is coordinated by CO and CN. We have synthesized dithiolate-bridged Ni-Fe complexes bearing CO and CN ligands to model the active center of [NiFe] hydrogenase. The Ni-Fe complexes containing a [(CN)2(CO)2Fe(μ-S2)NiS2] framework are the closest yet structural models of [NiFe] hydrogenase. Copyright © 2005 American Chemical Society.

引用

收藏

页码：8950 / 8951

页数：2

相关论文

共 40 条

[1] Biochemistry - Biological hydrogen production: Not so elementary [J].

Adams, MWW ;

Stiefel, EI .

SCIENCE, 1998, 282 (5395) :1842-1843

[2] PURIFICATION OF THE MEMBRANE-BOUND HYDROGENASE OF ESCHERICHIA-COLI [J].

ADAMS, MWW ;

HALL, DO .

BIOCHEMICAL JOURNAL, 1979, 183 (01) :11-22

[3] NICKEL HYDROGENASES - IN SEARCH OF THE ACTIVE-SITE [J].

ALBRACHT, SPJ .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1994, 1188 (03) :167-204

[4] Bioinorganic chemistry - Hydrogenase sophistication [J].

Cammack, R .

NATURE, 1999, 397 (6716) :214-215

[5] Preparative and structural studies on iron(II)-thiolate cyanocarbonyls: relevance to the [NiFe]/[Fe]-hydrogenases [J].

Chen, CH ;

Chang, YS ;

Yang, CY ;

Chen, TN ;

Lee, CM ;

Liaw, WF .

DALTON TRANSACTIONS, 2004, (01) :137-143

[6] MEASUREMENT INVIVO OF HYDROGENASE-CATALYZED HYDROGEN EVOLUTION IN THE PRESENCE OF NITROGENASE ENZYME IN CYANOBACTERIA [J].

DADAY, A ;

LAMBERT, GR ;

SMITH, GD .

BIOCHEMICAL JOURNAL, 1979, 177 (01) :139-144

[7] IR spectroelectrochemical study of the binding of carbon monoxide to the active site of Desulfovibrio fructosovorans Ni-Fe hydrogenase [J].

DeLacey, AL ;

Stadler, C ;

Fernandez, VM ;

Hatchikian, EC ;

Fan, HJ ;

Li, SH ;

Hall, MB .

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2002, 7 (03) :318-326

[8] Chemistry and the hydrogenases [J].

Evans, DJ ;

Pickett, CJ .

CHEMICAL SOCIETY REVIEWS, 2003, 32 (05) :268-275

[9]

Frey M., 2001, HDB METALLOPROTEINS, V2, P880

[10] The crystal structure of a reduced [NiFeSe] hydrogenase provides an image of the activated catalytic center [J].

Garcin, E ;

Vernede, X ;

Hatchikian, EC ;

Volbeda, A ;

Frey, M ;

Fontecilla-Camps, JC .

STRUCTURE WITH FOLDING & DESIGN, 1999, 7 (05) :557-566

← 1 2 3 4 →