Interstitial Lung Disease in the Connective Tissue Diseases

被引:41
作者
Antin-Ozerkis, Danielle [1 ]
Rubinowitz, Ami [2 ]
Evans, Janine [3 ]
Homer, Robert J.
Matthay, Richard A. [4 ]
机构
[1] Yale Univ, Dept Internal Med, Pulm & Crit Care Med Sect, Sch Med,Yale Interstitial Lung Dis Program, New Haven, CT 06510 USA
[2] Yale Univ, Sch Med, Dept Diagnost Radiol, New Haven, CT 06520 USA
[3] Yale Univ, Sch Med, Dept Internal Med, Rheumatol Sect, New Haven, CT 06520 USA
[4] Yale Univ, Sch Med, Dept Internal Med, Pulm & Crit Care Med Sect, New Haven, CT 06520 USA
关键词
Connective tissue; Interstitial lung disease; Inflammation; Immunity; SYSTEMIC-LUPUS-ERYTHEMATOSUS; RESOLUTION COMPUTED-TOMOGRAPHY; IDIOPATHIC PULMONARY-FIBROSIS; PRIMARY SJOGRENS-SYNDROME; OF-THE-LITERATURE; ACID GASTROESOPHAGEAL-REFLUX; DIFFUSE ALVEOLAR HEMORRHAGE; STEM-CELL TRANSPLANTATION; PLACEBO-CONTROLLED TRIAL; LOWER RESPIRATORY-TRACT;
D O I
10.1016/j.ccm.2012.01.004
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
100201 [内科学];
摘要
The connective tissue diseases (CTDs) are inflammatory, immune-mediated disorders in which interstitial lung disease (ILD) is common and clinically important. Interstitial lung disease may be the first manifestation of a CTD in a previously healthy patient. CTD-associated ILD frequently presents with the gradual onset of cough and dyspnea, although rarely may present with fulminant respiratory failure. Infection and drug reaction should always be ruled out. A diagnosis of idiopathic ILD should never be made without a careful search for subtle evidence of underlying CTD. Treatment of CTD-ILD typically includes corticosteroids and immunosuppressive agents.
引用
收藏
页码:123 / +
页数:28
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