Translational pharmacology: Harnessing increased specialization of research within the basic biological sciences

被引:6
作者
Anger, G. J. [1 ]
Piquette-Miller, M. [1 ]
机构
[1] Univ Toronto, Fac Pharm, Toronto, ON, Canada
关键词
D O I
10.1038/clpt.2008.83
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:797 / 801
页数:5
相关论文
共 11 条
[1]   Mathematics for understanding disease [J].
Bies, R. R. ;
Gastonguay, M. R. ;
Schwartz, S. L. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 83 (06) :904-908
[2]   From genome to drug lead: Identification of a small-molecule inhibitor of the SARS virus [J].
Dooley, AJ ;
Shindo, N ;
Taggart, B ;
Park, JG ;
Pang, YP .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (04) :830-833
[3]   Lazarus's gate: Challenges and potential of epigenetic reprogramming of somatic cells [J].
Henderson, J. T. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 83 (06) :889-893
[4]  
Kotler P., 1973, MULTIATTRIBUTE DECIS
[5]   What's next in translational medicine? [J].
Littman, Bruce H. ;
Di Mario, Linda ;
Plebani, Mario ;
Marincola, Francesco M. .
CLINICAL SCIENCE, 2007, 112 (3-4) :217-227
[6]   Development of translational pharmacokinetic-pharmacodynamic models [J].
Mager, D. E. ;
Jusko, W. J. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 83 (06) :909-912
[7]   Mice as clinically relevant models for the study of cytochrome P450-dependent metabolism [J].
Muruganandan, S. ;
Sinal, C. J. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 83 (06) :818-828
[8]   In silico drug discovery:: Solving the "target-rich and lead-poor" imbalance using the genome-to-drug-lead paradigm [J].
Pang, Y. P. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2007, 81 (01) :30-34
[9]   Animal studies in the development of medical countermeasures [J].
Roberts, R. ;
McCune, S. K. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 83 (06) :918-920
[10]   Inflammation and altered drug clearance in cancer: Transcriptional repression of a human CYP3A4 transgene in tumor-bearing mice [J].
Robertson, G. R. ;
Liddle, C. ;
Clarke, S. J. .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 83 (06) :894-897