Alkaloids from Piper sarmentosum and Piper nigrum

被引：59

作者：

Ee, G. C. L. ^{[1
]}

Lim, C. M. ^{[1
]}

Lim, C. K. ^{[2
]}

Rahmani, M. ^{[1
]}

Shaari, K. ^{[1
]}

Bong, C. F. J. ^{[3
]}

机构：

[1] Univ Putra Malaysia, Fac Sci, Dept Chem, Serdang 43400, Selangor, Malaysia

[2] Univ Tunku Abdul Rahman, Fac Engn & Sci, Kuala Lumpur 53300, Malaysia

[3] Univ Putra Malaysia, Fac Agr & Food Sci, Dept Crop Sci, Bintulu 97008, Sarawak, Malaysia

来源：

NATURAL PRODUCT RESEARCH | 2009年 / 23卷 / 15期

关键词：

Piper nigrum; Piper sarmentosum; alkaloids; cytotoxic; CHEMICAL-CONSTITUENTS; AMIDES;

D O I：

10.1080/14786410902757998

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Detailed chemical studies on the roots of Piper sarmentosum and Piper nigrum have resulted in several alkaloids. The roots of P. sarmentosum gave a new aromatic compound, 1-nitrosoimino-2,4,5-trimethoxybenzene (1). Piper nigrum roots gave pellitorine (2), (E)-1-[3',4'-(methylenedioxy)cinnamoyl]piperidine (3), 2,4-tetradecadienoic acid isobutyl amide (4), piperine (5), sylvamide (6), cepharadione A (7), piperolactam D (8) and paprazine (9). Structural elucidation of these compounds was achieved through NMR and MS techniques. Cytotoxic activity screening of the plant extracts indicated some activity.

引用

页码：1416 / 1423

页数：8

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