Celecoxib-related renal papillary necrosis

被引：27

作者：

Akhund, L ^{[1
]}

Quinet, RJ ^{[1
]}

Ishaq, S ^{[1
]}

机构：

[1] Alton Ochsner Med Fdn & Ochsner Clin, Dept Internal Med, Rheumatol Sect, New Orleans, LA 70121 USA

来源：

ARCHIVES OF INTERNAL MEDICINE | 2003年 / 163卷 / 01期

关键词：

D O I：

10.1001/archinte.163.1.114

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Selective cyclooxygenase 2 (COX-2) inhibitors are known to affect renal prostaglandins (epoprostenol and dinoprostone), which are at least in part COX-2 dependent. Consequently, adverse events including hypertension, peripheral edema, hypercalemia, hyponatremia, and acute renal failure have been reported to occur with the new COX-2-specific inhibitors. This case report posits celecoxib as a likely cause of renal papillary necrosis and alerts physicians to the possibility of this additional renal complication with COX-2-specific inhibitors.

引用

页码：114 / 115

页数：2