EVH1/WH1 domains of VASP and WASP proteins belong to a large family including Ran-binding domains of the RanBP1 family

被引：39

作者：

Callebaut, I

Cossart, P

Dehoux, P ^{[1
]}

机构：

[1] Univ Paris 06, LMCP, CNRS, UMRC 7590, Paris, France

[2] Univ Paris 07, LMCP, CNRS, UMRC 7590, Paris, France

[3] Inst Pasteur, Unite Interact Bacteries Cellules, F-75010 Paris, France

来源：

FEBS LETTERS | 1998年 / 441卷 / 02期

基金：

澳大利亚研究理事会;

关键词：

sequence analysis; polyproline; WH1; domain; EVH1;

D O I：

10.1016/S0014-5793(98)01541-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The two cytoskeletal proteins VASP and WASP and the protein Homer share a conserved domain, currently designated the WH1 domain (WASP homology domain I) or EVH1 domain (ENA/VASP homology domain 1), which could play an important role in various cellular events such as transport, folding of proteins, and signal transduction. We report here additional occurrences of this domain in Ran-binding proteins of the RanBP1 family and various others proteins, or putative proteins of eukaryotic organisms, suggesting that the EVH1/WH1 domain may be more widely used than originally thought. (C) 1998 Federation of European Biochemical Societies.

引用

页码：181 / 185

页数：5

共 38 条

[1] Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains
Ahern-Djamali, SM
Conner, AR
Bachmann, C
Kastenmeier, AS
Reddy, SK
Beckerle, MC
Walter, U
Hoffmann, FM
[J]. MOLECULAR BIOLOGY OF THE CELL, 1998, 9 (08) : 2157 - 2171
[2] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
Altschul, SF
Madden, TL
Schaffer, AA
Zhang, JH
Zhang, Z
Miller, W
Lipman, DJ
[J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (17) : 3389 - 3402
[3] The PROSITE database, its status in 1997
Bairoch, A
Bucher, P
Hofmann, K
[J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (01) : 217 - 221
[4] THE RAN/TC4 GTPASE-BINDING DOMAIN - IDENTIFICATION BY EXPRESSION CLONING AND CHARACTERIZATION OF A CONSERVED SEQUENCE MOTIF
BEDDOW, AL
RICHARDS, SA
OREM, NR
MACARA, IG
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (08) : 3328 - 3332
[5] COACTIVATION OF RANGTPASE AND INHIBITION OF GTP DISSOCIATION BY RAN GTP-BINDING PROTEIN RANBP1
BISCHOFF, FR
KREBBER, H
SMIRNOVA, E
DONG, WH
PONSTINGL, H
[J]. EMBO JOURNAL, 1995, 14 (04) : 705 - 715
[6] Homer: A protein that selectively binds metabotropic glutamate receptors
Brakeman, PR
Lanahan, AA
OBrien, R
Roche, K
Barnes, CA
Huganir, RL
Worley, PF
[J]. NATURE, 1997, 386 (6622) : 284 - 288
[7] From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair
Callebaut, I
Mornon, JP
[J]. FEBS LETTERS, 1997, 400 (01): : 25 - 30
[8] Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives
Callebaut, I
Labesse, G
Durand, P
Poupon, A
Canard, L
Chomilier, J
Henrissat, B
Mornon, JP
[J]. CELLULAR AND MOLECULAR LIFE SCIENCES, 1997, 53 (08) : 621 - 645
[9] Functions of the GTPase ran in RNA export from the nucleus
Dahlberg, JE
Lund, E
[J]. CURRENT OPINION IN CELL BIOLOGY, 1998, 10 (03) : 400 - 408
[10] A Drosophila gene regulated by rough and glass shows similarity to ena and VASP
DeMille, MMC
Kimmel, BE
Rubin, GM
[J]. GENE, 1996, 183 (1-2) : 103 - 108

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