A disposable single-use electrochemical sensor for the detection of uric acid in human whole blood

被引：105

作者：

Chen, JC ^{[1
]}

Chung, HH ^{[1
]}

Hsu, CT ^{[1
]}

Tsai, DM ^{[1
]}

Kumar, AS ^{[1
]}

Zen, JM ^{[1
]}

机构：

[1] Natl Chung Hsing Univ, Dept Chem, Taichung 402, Taiwan

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2005年 / 110卷 / 02期

关键词：

screen-printed electrode; single-use electrochemical sensors; uric acid; whole blood; electrochemical test strip;

D O I：

10.1016/j.snb.2005.02.026

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We report here a non-enzymatic detecting electrode strip for fast monitoring of uric acid in human whole blood. A single-use amperometric uric acid sensor strip, incorporating a three-electrode configuration, has been fabricated on a polypropylene substrate using low cost screen-printing (thick-film) technology. Both the working and counter electrodes were prepared by screen-printing commercial carbon ink. The integration on the same support of pseudo-reference electrode was obtained by screen-printing a commercial silver ink and subsequent electrochemical pretreatment. Simply by placing a 20 mu l human whole blood drop on the strip is enough for uric acid analysis by square-wave voltammetry. Real human whole blood samples were analyzed by this method and compared to the phosphotungstic acid clinical test procedure with satisfactory results. (C) 2005 Elsevier B.V. All rights reserved.

引用

页码：364 / 369

页数：6

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