LightTyper assay with locked-nucleic-acid-modified oligomers for genotyping of the toll-like receptor 4 Polymorphisms A896G and C1196T

被引：6

作者：

Grannemann, S

Landt, F

Breuer, S

Blömeke, B

机构：

[1] Univ Trier, Dept Ecotoxicol Toxicol, D-54296 Trier, Germany

[2] Univ Hosp, Rhein Westfal TH Aachen, Dept Dermatol & Allergol, D-5100 Aachen, Germany

[3] TIB MOLBIOL Syntheselabor GmbH, Berlin, Germany

来源：

CLINICAL CHEMISTRY | 2005年 / 51卷 / 08期

关键词：

D O I：

10.1373/clinchem.2005.049197

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

[No abstract available]

引用

页码：1523 / 1525

页数：3

共 12 条

[1] TLR4 mutations are associated with endotoxin hyporesponsiveness in humans [J].

Arbour, NC ;

Lorenz, E ;

Schutte, BC ;

Zabner, J ;

Kline, JN ;

Jones, M ;

Frees, K ;

Watt, JL ;

Schwartz, DA .

NATURE GENETICS, 2000, 25 (02) :187-+

[2] Genotyping of the triallelic variant G2677T/A in MDR1 using LightCycler with locked-nucleic-acid-modified hybridization probes [J].

Arjomand-Nahad, F ;

Diefenbach, K ;

Landt, O ;

Gaikovitch, E ;

Roots, I .

ANALYTICAL BIOCHEMISTRY, 2004, 334 (01) :201-203

[3] Deficient host-bacteria interactions in inflammatory bowel disease?: The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis [J].

Franchimont, D ;

Vermeire, S ;

El Housni, H ;

Pierik, M ;

Van Steen, K ;

Gustot, T ;

Quertinmont, E ;

Abramowicz, M ;

Van Gossum, A ;

Devière, J ;

Rutgeerts, P .

GUT, 2004, 53 (07) :987-992

[4] Rapid and inexpensive real-time PCR for genotyping functional polymorphisms within the Toll-like receptor-2,-4, and-9 genes [J].

Hamann, L ;

Hamprecht, A ;

Gomma, A ;

Schumann, RR .

JOURNAL OF IMMUNOLOGICAL METHODS, 2004, 285 (02) :281-291

[5] Rapid and reliable genotyping for the Toll-like receptor 4 A896G polymorphism using fluorescence-labeled hybridization probes in a real-time polymerase chain reaction assay [J].

Heesen, M ;

Wessiepe, M ;

Kunz, D ;

Vasickova, K ;

Blomeke, B .

CLINICA CHIMICA ACTA, 2003, 333 (01) :47-49

[6] Determination of the TLR4 genotype using allele-specific PCR [J].

Lorenz, E ;

Frees, KL ;

Schwartz, DA .

BIOTECHNIQUES, 2001, 31 (01) :22-24

[7] Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings [J].

Michel, O ;

LeVan, TD ;

Stern, D ;

Dentener, M ;

Thorn, J ;

Gnat, D ;

Beijer, ML ;

Cochaux, P ;

Holt, PG ;

Martinez, FD ;

Rylander, R .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2003, 112 (05) :923-929

[8] Single nucleotide polymorphism genotyping using locked nucleic acid (LNA™) [J].

Mouritzen, P ;

Nielsen, AT ;

Pfundheller, HM ;

Choleva, Y ;

Kongsbak, L ;

Moller, S .

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 2003, 3 (01) :27-38

[9] Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells [J].

Muzio, M ;

Bosisio, D ;

Polentarutti, N ;

D'amico, G ;

Stoppacciaro, A ;

Mancinelli, R ;

van't Veer, C ;

Penton-Rol, G ;

Ruco, LP ;

Allavena, P ;

Mantovani, A .

JOURNAL OF IMMUNOLOGY, 2000, 164 (11) :5998-6004

[10] Simple genotype analysis of the Asp299Gly polymorphism of the Toll-like receptor-4 gene that is associated with lipopolysaccharide hyporesponsiveness [J].

Okayama, N ;

Fujimura, K ;

Suehiro, Y ;

Hamanaka, Y ;

Fujiwara, M ;

Matsubara, T ;

Maekawa, T ;

Hazama, S ;

Oka, M ;

Nohara, H ;

Kayano, K ;

Okita, K ;

Hinoda, Y .

JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2002, 16 (01) :56-58

← 1 2 →