Combinatorial microscopy

被引:27
作者
Axelrod, Daniel [1 ]
Omann, Geneva M.
机构
[1] Univ Michigan, Dept Phys, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Div Biophys Res, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Biol Chem, Ann Arbor, MI 48109 USA
[4] Univ Michigan, Dept Surg, Ann Arbor, MI 48109 USA
[5] Vet Adm Med Ctr, Ann Arbor, MI 48109 USA
关键词
D O I
10.1038/nrm2062
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
By taking advantage of combinations of the many rich properties of photons, new forms of optical microscopy can now be used to visualize features of samples beyond thickness and density variations. We are now within reach of viewing the motions, orientations, binding kinetics and specific transient associations of previously 'submicroscopic' cellular structures and single molecules.
引用
收藏
页码:944 / 952
页数:9
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