The genetic and molecular mechanisms of motor neuron disease

被引：57

作者：

Wong, PC

Rothstein, JD

Price, DL

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA

[2] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA

[3] Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21205 USA

[4] Johns Hopkins Univ, Sch Med, Dept Cellular & Mol Med, Baltimore, MD 21205 USA

[5] Johns Hopkins Univ, Sch Med, Div Neuropathol, Baltimore, MD 21205 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 1998年 / 8卷 / 06期

关键词：

D O I：

10.1016/S0959-4388(98)80123-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Significant progress has been made in the identification of genes and chromosomal loci associated with several types of motor neuron disease. Of particular interest is recent work on the pathogenic mechanisms underlying these diseases, especially studies in in vitro model systems and in transgenic and gene-targeted mice.

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收藏

页码：791 / 799

页数：9

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