Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3

被引:675
作者
Sung, SB [1 ]
Amasino, RM [1 ]
机构
[1] Univ Wisconsin, Dept Biochem, Madison, WI 53706 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
D O I
10.1038/nature02195
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
In biennials and winter annuals, flowering is typically blocked in the first growing season. Exposure to the prolonged cold of winter, through a process called vernalization, is required to alleviate this block and permit flowering in the second growing season(1). In winter-annual types of Arabidopsis thaliana, a flowering repressor, FLOWERING LOCUS C (FLC), is expressed at levels that inhibit flowering in the first growing season(2). Vernalization promotes flowering by causing a repression of FLC that is mitotically stable after return to warmgrowing conditions(2). Here we identify a gene with a function in the measurement of the duration of cold exposure and in the establishment of the vernalized state. We show that this silencing involves changes in the modification of histones in FLC chromatin.
引用
收藏
页码:159 / 164
页数:6
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