Zinc-mediated asymmetric epoxidation of nitro alkenes with oxygen

被引：31

作者：

Enders, D ^{[1
]}

Kramps, L ^{[1
]}

Zhu, JQ ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 22期

关键词：

D O I：

10.1016/S0957-4166(98)00424-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The asymmetric epoxidation of nitro alkenes using oxygen in the presence of diethylzinc and N-methyl pseudoephedrine as a chiral additive is reported. This method provides an access to 3-substituted trans-2-nitro oxiranes of excellent diastereomeric purity (de greater than or equal to 98%) and with medium to good enantiomeric excesses (ee=36-82%). (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3959 / 3962

页数：4

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