microRNAs as peripheral blood biomarkers of cardiovascular disease

被引：62

作者：

Di Stefano, Valeria ^{[2
]}

Zaccagnini, Germana ^{[1
]}

Capogrossi, Maurizio C. ^{[1
]}

Martelli, Fabio ^{[1
]}

机构：

[1] Ist Dermopat Immacolata IRCCS, Lab Atol Vasc, I-00167 Rome, Italy

[2] IRCCS Policlin San Donato, Mol Cardiol Lab, I-20097 San Donato Milanese, Milan, Italy

来源：

VASCULAR PHARMACOLOGY | 2011年 / 55卷 / 04期

关键词：

microRNA; Biomarker; Peripheral blood; Cardiovascular disease; MUSCLE-SPECIFIC MICRORNA; CIRCULATING MICRORNAS; SMALL RNAS; PLASMA; SERUM; EXPRESSION; HEART; DICER; BIOGENESIS; SIGNATURE;

D O I：

10.1016/j.vph.2011.08.001

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A host of studies have established essential roles for microRNAs in cardiovascular development and disease. Moreover, the discovery of stable microRNAs in bodily fluids indicated their potential as non-invasive biomarkers. In this review, we summarize the current studies describing microRNAs in blood cells or serum/plasma, as potential biomarkers of cardiovascular disease. (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：111 / 118

页数：8

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