Proton and carbon-13 NMR assignments of 3,4-methylenedioxyamphetamine (MDA) and some analogues of MDA

被引：8

作者：

DalCason, TA ^{[1
]}

Meyers, JA ^{[1
]}

Lankin, DC ^{[1
]}

机构：

[1] GD SEARLE & CO, SKOKIE, IL 60077 USA

来源：

FORENSIC SCIENCE INTERNATIONAL | 1997年 / 86卷 / 1-2期

关键词：

3,4-methylenedioxyamphetamine; nitrogen-substituted MDA analogues; nuclear magnetic resonance;

D O I：

10.1016/S0379-0738(97)02102-6

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Characterization of MDA (3,4-methylenedioxyamphetamine) and a series of nitrogen-substituted MDA analogues has been studied using proton and carbon-13 NMR spectroscopy, The H-1 and C-13 chemical shift assignments for both have been confirmed using a combination of 1-dimensional and 2-dimensional NMR experiments. The chemical shift trends of the side chain carbon resonances (alpha-CH2, beta-CH, and gamma-CH3) for MDA, N-methyl MDA and N,N-dimethyl MDA, as both free bases and hydrochloride salts, have been examined. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：15 / 24

页数：10

共 15 条

[1] A SIMPLE METHOD FOR SUPPRESSING DISPERSION-MODE CONTRIBUTIONS IN NMR-SPECTRA - THE PSEUDO ECHO [J].