In thymic selection, peptide diversity gives and takes away

被引:111
作者
Bevan, MJ
机构
[1] Howard Hughes Medical Institute, Department of Immunology, University of Washington, Seattle
关键词
D O I
10.1016/S1074-7613(00)80520-8
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:175 / 178
页数:4
相关论文
共 15 条
[1]   T-cell-receptor affinity and thymocyte positive selection [J].
Alam, SM ;
Travers, PJ ;
Wung, JL ;
Nasholds, W ;
Redpath, S ;
Jameson, SC ;
Gascoigne, NRJ .
NATURE, 1996, 381 (6583) :616-620
[2]  
FINK PJ, 1995, ADV IMMUNOL, V59, P99, DOI 10.1016/S0065-2776(08)60630-6
[3]   Positive and negative CD4(+) thymocyte selection by a single MHC clas II peptide ligand affected by its expression level in the thymus [J].
Fukui, Y ;
Ishimoto, T ;
Utsuyama, M ;
Gyotoku, T ;
Koga, T ;
Nakao, K ;
Hirokawa, K ;
Katsuki, M ;
Sasazuki, T .
IMMUNITY, 1997, 6 (04) :401-410
[4]   Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides [J].
Grubin, CE ;
Kovats, S ;
deRoos, P ;
Rudensky, AY .
IMMUNITY, 1997, 7 (02) :197-208
[5]   Identification of a naturally occurring ligand for thymic positive selection [J].
Hogquist, KA ;
Tomlinson, AJ ;
Kieper, WC ;
McGargill, MA ;
Hart, MC ;
Naylor, S ;
Jameson, SC .
IMMUNITY, 1997, 6 (04) :389-399
[6]   Specific recognition of thymic self-peptides induces the positive selection of cytotoxic T lymphocytes [J].
Hu, QH ;
Walker, CRB ;
Girao, C ;
Opferman, JT ;
Sun, JL ;
Shabanowitz, J ;
Hunt, DF ;
AshtonRickardt, PG .
IMMUNITY, 1997, 7 (02) :221-231
[7]   T cells can be activated by peptides that are unrelated in sequence to their selecting peptide [J].
Ignatowicz, L ;
Rees, W ;
Pacholczyk, R ;
Ignatowicz, H ;
Kushnir, E ;
Kappler, J ;
Marrack, P .
IMMUNITY, 1997, 7 (02) :179-186
[8]   The repertoire of T cells shaped by a single MHC/peptide ligand [J].
Ignatowicz, L ;
Kappler, J ;
Marrack, P .
CELL, 1996, 84 (04) :521-529
[9]  
JAMESON SC, 1995, ANNU REV IMMUNOL, V13, P93, DOI 10.1146/annurev.iy.13.040195.000521
[10]   Essential flexibility in the T-cell recognition of antigen [J].
Kersh, GJ ;
Allen, PM .
NATURE, 1996, 380 (6574) :495-498