Neurohormonal response to head-up tilt and its role in vasovagal syncope

被引：58

作者：

Jardine, DL ^{[1
]}

Melton, IC ^{[1
]}

Crozier, IG ^{[1
]}

Bennett, SI ^{[1
]}

Donald, RA ^{[1
]}

Ikram, H ^{[1
]}

机构：

[1] CHRISTCHURCH HOSP,DEPT CARDIOL,CHRISTCHURCH,NEW ZEALAND

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1997年 / 79卷 / 09期

关键词：

ATRIAL-NATRIURETIC-PEPTIDE; VASOPRESSIN; HUMANS; ANGIOTENSIN; BAROREFLEX; INCREASE; PRESSURE; RELEASE;

D O I：

10.1016/S0002-9149(9X)00084-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In a controlled study, 26 patients with a history of recurrent syncope were found to have increased arginine vasopressin, corticotrophin, and atrial natriuretic factor levels after 5 minutes of 60 degrees head-up tilt, long before they became hypotensive. The exaggerated neurohormonal response in these patients may indicate a greater sensitivity to central hypovolemia which may predispose to vasovagal syncope, mediated by the vasodilatory effects of atrial natriuretic factor or the sensitization of mechanoreceptors by arginine vasopressin.

引用

页码：1302 / &

页数：6

共 20 条

[1] EFFECTS OF VASOPRESSIN ON THE CIRCULATION AND ITS BAROREFLEX CONTROL IN HEALTHY-MEN [J].

AYLWARD, PE ;

FLORAS, JS ;

LEIMBACH, WN ;

ABBOUD, FM .

CIRCULATION, 1986, 73 (06) :1145-1154

[2] TILT TABLE TESTING FOR EVALUATION OF NEURALLY-MEDIATED (CARDIONEUROGENIC) SYNCOPE - RATIONALE AND PROPOSED PROTOCOLS [J].

BENDITT, DG ;

REMOLE, S ;

BAILIN, S ;

DUNNIGAN, A ;

ASSO, A ;

MILSTEIN, S .

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1991, 14 (10) :1528-1537

[3]

COWLEY AW, 1982, INT REV PHYSIOL, V26, P189

[4] OSMOTICALLY RELEASED VASOPRESSIN AUGMENTS CARDIOPULMONARY REFLEX INHIBITION OF THE CIRCULATION [J].

HASSER, EM ;

DICARLO, SE ;

APPLEGATE, RJ ;

BISHOP, VS .

AMERICAN JOURNAL OF PHYSIOLOGY, 1988, 254 (05) :R815-R820

[5] CAROTID BAROREFLEXES AND PLASMA VASOPRESSIN IN HUMANS DURING HEAD-UP TILT [J].

KAMEGAI, M ;

KRISTENSEN, MS ;

WARBERG, J ;

NORSK, P .

AMERICAN JOURNAL OF PHYSIOLOGY, 1992, 263 (02) :R318-R323

[6] EFFECTS OF GUANETHIDINE RESERPINE + METHYLDOPA ON REFLEX VENOUS + ARTERIAL CONSTRICTION IN MAN [J].

MASON, DT ;

BRAUNWALD, E ;

KING, CV ;

KARSH, RB ;

KRUEGER, DD .

JOURNAL OF CLINICAL INVESTIGATION, 1964, 43 (07) :1449-&

[7] AUGMENTATION OF THE RESPONSE TO CRF IN MAN - RELATIVE CONTRIBUTIONS OF ENDOGENOUS ANGIOTENSIN AND VASOPRESSIN [J].

MILSOM, SR ;

CONAGLEN, JV ;

DONALD, RA ;

ESPINER, EA ;

NICHOLLS, MG ;

LIVESEY, JH .

CLINICAL ENDOCRINOLOGY, 1985, 22 (05) :623-628

[8] IMPAIRMENT OF CARDIOPULMONARY BAROREFLEX AFTER CARDIAC TRANSPLANTATION IN HUMANS [J].

MOHANTY, PK ;

THAMES, MD ;

ARROWOOD, JA ;

SOWERS, JR ;

MCNAMARA, C ;

SZENTPETERY, S .

CIRCULATION, 1987, 75 (05) :914-921

[9] VENOUS PLETHYSMOGRAPHY - MEASURING TECHNIQUES AND NORMAL VALUES [J].

POINTEL, JP ;

GIN, H ;

DROUIN, P ;

VERNHES, G ;

DEBRY, G .

ANGIOLOGY, 1981, 32 (03) :145-154

[10] ANGIOTENSIN-II INFUSION INCREASES VASOPRESSIN, ACTH, AND 11-HYDROXYCORTICOSTEROID SECRETION [J].

RAMSAY, DJ ;

KEIL, LC ;

SHARPE, MC ;

SHINSAKO, J .

AMERICAN JOURNAL OF PHYSIOLOGY, 1978, 234 (01) :R66-R71

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