Increases in clitoral and vaginal blood flow following clitoral and pelvic plexus nerve stimulations in the female rat

被引:41
作者
Vachon, P [1 ]
Simmerman, N [1 ]
Zahran, AR [1 ]
Carrier, S [1 ]
机构
[1] McGill Univ, Sir Mortimer B Davis Jewish Hosp, Lady Davis Inst Med Res, Dept Med, Montreal, PQ H3T 1E2, Canada
关键词
rat; female; blood flow; laser Doppler; nerve stimulation;
D O I
10.1038/sj.ijir.3900480
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The objective of this present study is to establish a model in the rat for the study of female clitoral and vaginal vascular changes during sexual excitation. A laser Doppler was used to measure blood flow changes following clitoral and pelvic plexus nerve stimulations. Results show an increase in clitoral blood flow following clitoral nerve (df(1) = 12, df(2) = 108, F = 21.4, P < 0.001) and pelvic plexus nerve stimulations (n = 3). A vaginal blood flow increase is also observed following pelvic plexus nerve stimulations (df(1) = 12, df(2) = 108, F = 4.75, P < 0.001). The female rat can therefore be used as a model for the study of the physiology, pharmacology and sexual dysfunction relating to blood flow in clitoral and vaginal tissue.
引用
收藏
页码:53 / 57
页数:5
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