ITAM multiplicity and thymocyte selection: How low can you go?

被引：70

作者：

Love, PE

Shores, EW ^{[1
]}

机构：

[1] US FDA, Div Therapeut Prot, Ctr Biol Evaluat & Res, Bethesda, MD 20892 USA

[2] NICHHD, Lab Mammalian Genes & Dev, NIH, Bethesda, MD 20892 USA

来源：

IMMUNITY | 2000年 / 12卷 / 06期

关键词：

D O I：

10.1016/S1074-7613(00)80210-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：591 / 597

页数：7

共 76 条

[1] Specific activation of the cysteine protease CPP32 during the negative selection of T cells in the thymus [J].

Alam, A ;

Braun, MY ;

Hartgers, F ;

Lesage, S ;

Cohen, L ;

Hugo, P ;

Denis, F ;

Sekaly, RP .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (09) :1503-1512

[2] T-cell-receptor affinity and thymocyte positive selection [J].

Alam, SM ;

Travers, PJ ;

Wung, JL ;

Nasholds, W ;

Redpath, S ;

Jameson, SC ;

Gascoigne, NRJ .

NATURE, 1996, 381 (6583) :616-620

[3] Positive and negative selection invoke distinct signaling pathways [J].

AlberolaIla, J ;

Hogquist, KA ;

Swan, KA ;

Bevan, MJ ;

Perlmutter, RM .

JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (01) :9-18

[4] SELECTIVE REQUIREMENT FOR MAP KINASE ACTIVATION IN THYMOCYTE DIFFERENTIATION [J].

ALBEROLAILA, J ;

FORBUSH, KA ;

SEGER, R ;

KREBS, EG ;

PERLMUTTER, RM .

NATURE, 1995, 373 (6515) :620-623

[5] Crippling of CD3-ζ ITAMs does not impair T cell receptor signaling [J].

Ardouin, L ;

Boyer, C ;

Gillet, A ;

Trucy, J ;

Bernard, AM ;

Nunes, J ;

Delon, J ;

Trautmann, A ;

He, HT ;

Malissen, B ;

Malissen, M .

IMMUNITY, 1999, 10 (04) :409-420

[6] ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4+8+ thymocytes with limiting p56lck [J].

Ashe, JM ;

Wiest, DL ;

Abe, R ;

Singer, A .

JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (07) :1163-1167

[7]

CALNAN BJ, 1995, IMMUNITY, V3, P273

[8] The tyrosine phosphatase SHP-1 influences thymocyte selection by setting TCR signaling thresholds [J].

Carter, JD ;

Neel, BG ;

Lorenz, U .

INTERNATIONAL IMMUNOLOGY, 1999, 11 (12) :1999-2013

[9] Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis [J].

Cheng, LEC ;

Chan, FKM ;

Cado, D ;

Winoto, A .

EMBO JOURNAL, 1997, 16 (08) :1865-1875

[10] T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: The molecular basis of negative selection [J].

Clayton, LK ;

Ghendler, Y ;

Mizoguchi, E ;

Patch, RJ ;

Ocain, TD ;

Orth, K ;

Bhan, AK ;

Dixit, VM ;

Reinherz, EL .

EMBO JOURNAL, 1997, 16 (09) :2282-2293

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