An ultrasensitive DNAzyme-based colorimetric strategy for nucleic acid detection

被引：41

作者：

Fu, Rongzhan ^{[1
]}

Li, Taihua ^{[1
]}

Park, Hyun Gyu ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Chem & Biomol Engn, Taejon 305701, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 39期

关键词：

DNA-ENZYME; NANOPARTICLES; DIAGNOSIS; CLEAVAGE; GENE; PCR;

D O I：

10.1039/b907762f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An ultrasensitive DNAzyme-based colorimetric DNA detection strategy was developed by utilizing gold nanoparticles modified with both peroxidase-mimicking DNAzymes and capture DNAs and magnetic nanoparticles modified with another capture DNAs, with a detection limit for a model Chlamydia gene of 50 fM.

引用

页码：5838 / 5840

页数：3

共 30 条

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