Microtubule modification: Acetylation speeds anterograde traffic flow

被引:63
作者
Sigala, Rodrigo [1 ]
Rainer, Gregor [1 ]
机构
[1] Columbia Univ, Sherman Fairchild Ctr, New York, NY 10027 USA
关键词
D O I
10.1016/j.cub.2006.11.036
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
Microtubules in neurites undergo multiple post-translational modifications. Recent work shows that neurites enriched in acetylated microtubules selectively support kinesin-mediated transport of the JNK regulator JIP-1 to growth cones.
引用
收藏
页码:R18 / R20
页数:3
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