Palladium-catalyzed cross-coupling reaction of alkenyl bromides with potassium alkyltrifluoroborates

被引：34

作者：

Molander, Gary A.

Ham, Jungyeob

Seapy, Dave G.

机构：

[1] Univ Penn, Dept Chem, Roy & Diana Vagelos Labs, Philadelphia, PA 19104 USA

[2] Eastern Univ, Dept Chem, St Davids, PA 19087 USA

来源：

TETRAHEDRON | 2007年 / 63卷 / 03期

关键词：

D O I：

10.1016/j.tet.2006.10.088

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Suzuki-Miyaura-type cross-coupling reaction of potassium alkyltrifluoroborates with various alkenyl bromides in the presence of 10 mol % of PdCl2(dppf)center dot CH2Cl2 and 3.0 equiv of Cs2CO3 in aqueous toluene at 80 degrees C provided the desired compounds in 63-95% yields. A variety of functional groups in the potassium alkyltrifluoroborates were tolerated under the basic conditions. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：768 / 775

页数：8

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