Pharmacokinetics of ketoprofen in the donkey (Equus asinus)

被引：12

作者：

Oukessou, M

Bouljihad, M

VanGool, F

Alvinerie, M

机构：

[1] Inst. Agronom. Veterinaire Hassan II, Rabat

[2] Inst. Agronom. Veterinaire Hassan II, Rabat

[3] Rhône Mérieux, Lyon

[4] Station de Pharmacologie-Toxicologie, INRA, Toulouse

来源：

JOURNAL OF VETERINARY MEDICINE SERIES A-ZENTRALBLATT FUR VETERINARMEDIZIN REIHE A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE | 1996年 / 43卷 / 07期

关键词：

D O I：

10.1111/j.1439-0442.1996.tb00470.x

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The pharmacokinetic parameters of ketoprofen were determined in four donkeys after a single intravenous injection of a dose of 2.2 mg/kg body weight. The total body clearance (Cl-B) was 414.0 +/- 98.70 ml/h/kg (mean +/- SD), the volume of distribution at steady state (V-5S) 263.10 +/- 55.43 ml/kg and the elimination half-life 1.30 +/- 0.75 h. These values were compared to those obtained in horses.

引用

页码：423 / 426

页数：4

共 14 条

[1]

GIBALDI M, 1987, PHARMACOKINETICS

[2] DISPOSITION OF OXYTETRACYCLINE IN HORSES, PONIES AND DONKEYS AFTER INTRAVENOUS ADMINISTRATION [J].