Gadolinium deposition in nephrogenic fibrosing dermopathy

被引:314
作者
Boyd, Alan S.
Zic, John A.
Abraham, Jerrold L.
机构
[1] Vanderbilt Univ, Dept Med Dermatol, Nashville, TN USA
[2] Vanderbilt Univ, Dept Pathol, Nashville, TN USA
[3] SUNy Upstate Med Univ, Dept Pathol, Syracuse, NY USA
关键词
D O I
10.1016/j.jaad.2006.10.048
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
There is growing recognition of the association between the use of gadolinium-containing radiocontrast agents for magnetic resonance imaging and the serious dermal and systemic disease nephrogenic fibrosing dermopathy/nephrogenic Systemic fibrosis (NFD/NSF), The pathogenesis of this entity remains unclear, however, our recent observations Suggest a likely mechanism for the initial dermal manifestations of this gadolinium toxicity.
引用
收藏
页码:27 / 30
页数:4
相关论文
共 10 条
[1]   Editorial: Nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis - Setting the record straight [J].
Cowper, SE ;
Bucala, R ;
Leboit, PE .
SEMINARS IN ARTHRITIS AND RHEUMATISM, 2006, 35 (04) :208-210
[2]   Nephrogenic fibrosing dermopathy [J].
Cowper, SE ;
Su, LD ;
Bhawan, J ;
Robin, HS ;
LeBoit, PE .
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2001, 23 (05) :383-393
[3]   Scleromyxoedema-like cutaneous diseases in renal-dialysis patients [J].
Cowper, SE ;
Robin, HS ;
Steinberg, SM ;
Su, LD ;
Gupta, S ;
LeBoit, PE .
LANCET, 2000, 356 (9234) :1000-1001
[4]  
*CTR DRUG EV RES, 2006, US FDA WEB SIT PUBL
[5]   Gadolinium - a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis? [J].
Grobner, T .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2006, 21 (04) :1104-1108
[6]   Nephrogenic systemic fibrosis: Suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging [J].
Marckmann, Peter ;
Skov, Lone ;
Rossen, Kristian ;
Dupont, Anders ;
Damholt, Mette Brimnes ;
Heaf, James Goya ;
Thomsen, Henrik S. .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2006, 17 (09) :2359-2362
[7]   Description of 12 cases of nephrogenic fibrosing dermopathy and review of the literature [J].
Mendoza, FA ;
Artlett, CM ;
Sandorfi, N ;
Latinis, K ;
Piera-Velazquez, S ;
Jimenez, SA .
SEMINARS IN ARTHRITIS AND RHEUMATISM, 2006, 35 (04) :238-249
[8]   Presence of CD45RO+ CD34+ cells with collagen synthesis activity in nephrogenic fibrosing dermopathy: a new pathogenic hypothesis [J].
Ortonne, N ;
Lipsker, D ;
Chantrel, F ;
Boehm, N ;
Grosshans, E ;
Cribier, B .
BRITISH JOURNAL OF DERMATOLOGY, 2004, 150 (05) :1050-1052
[9]   Gadolinium chloride toxicity in the rat [J].
Spencer, AJ ;
Wilson, SA ;
Batchelor, J ;
Reid, A ;
Rees, J ;
Harpur, E .
TOXICOLOGIC PATHOLOGY, 1997, 25 (03) :245-255
[10]   Nephrogenic fibrosing dermopathy with systemic involvement [J].
Ting, WW ;
Stone, MS ;
Madison, KC ;
Kurtz, K .
ARCHIVES OF DERMATOLOGY, 2003, 139 (07) :903-906