Genetics of the renin-angiotensin system and renal disease: A progress report

被引：46

作者：

Schmidt, S

Ritz, E

机构：

[1] Department of Internal Medicine, Division of Nephrology, University of Heidelberg, Heidelberg

[2] Department of Internal Medicine, Division of Nephrology, University of Heidelberg, 69115 Heidelberg

来源：

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION | 1997年 / 6卷 / 02期

关键词：

D O I：

10.1097/00041552-199703000-00007

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The genes of the renin-angiotensin system and their relation to renal diseases are of great interest. The number of studies examining the role of polymorphism in these genes in development or progression of renal diseases has increased nearly logarithmically, but results remain conflicting. Evidence is increasing that progression of renal disease is more rapid in DD-homozygotes of the angiotensin-converting enzyme gene polymorphism, but other relationships have not been solidly established.

引用

页码：146 / 151

页数：6

共 57 条

[1]

BARLEY J, 1994, J HYPERTENS, V12, P955

[2]

BARNAS U, 1995, J AM SOC NEPHROL, V6, P1036

[3]

BILO HJG, 1995, J AM SOC NEPHROL, V6, P1037

[4]

Bourbigot B., 1996, Journal of the American Society of Nephrology, V7, P1903

[5]

Broekroelofs J., 1996, Journal of the American Society of Nephrology, V7, P1903

[6]

Cheong Hae Il, 1996, Journal of the American Society of Nephrology, V7, P1383

[7]

Doi Y, 1996, DIABETOLOGIA, V39, P97

[8] Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes [J].

Doria, A ;

Onuma, T ;

Gearin, G ;

Freire, MBS ;

Warram, JH ;

Krolewski, AS .

HYPERTENSION, 1996, 27 (05) :1134-1139

[9] UK PROSPECTIVE DIABETES STUDY .15. RELATIONSHIP OF RENIN-ANGIOTENSIN SYSTEM GENE POLYMORPHISMS WITH MICROALBUMINURIA IN NIDDM [J].

DUDLEY, CRK ;

KEAVNEY, B ;

STRATTON, IM ;

TURNER, RC ;

RATCLIFFE, PJ .

KIDNEY INTERNATIONAL, 1995, 48 (06) :1907-1911

[10]

FOGARTY DG, 1995, J AM SOC NEPHROL, V6, P449

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