Ligand scrambling reactions of cyano(thione)gold(I) complexes and determination of their equilibrium constants

被引：72

作者：

Ahmad, S ^{[1
]}

Isab, AA ^{[1
]}

Perzanowski, HP ^{[1
]}

机构：

[1] King Fahd Univ Petr & Minerals, Dept Chem, Dhahran 31261, Saudi Arabia

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 2002年 / 80卷 / 10期

关键词：

cyanogold(I) complexes; thiones; ligand scrambling; NMR; K-eq;

D O I：

10.1139/V02-165

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ligand scrambling reactions in cyano(thione)gold(I) complexes ([>C=S-Au-CN]) to form [Au(>C=S)(2)](+) and [Au(CN)(2)](-) species have been investigated for a series of thiones in DMSO using C-13 and N-15 NMR spectroscopy. Rapid approach to equilibrium occurred and resulted in distinct signals for the [>C=S-Au-CN] and [Au(CN)(2)](-) complexes, both in C-13 and N-15 NMR. Equilibrium constants (K-eq) were determined for scrambling of all the complexes by integrating the CN resonances in the C-13 NMR recorded at 298 K. The influence of various factors (initial concentration, ionic strength, temperature, and solvent polarity) on the K-eq value was examined for a representative complex (ImtAuCN (Imt = Imidazolidine-2-thione)).

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页码：1279 / 1284

页数：6

相关论文

共 26 条

[1] Gold(I) complexes with tertiary phosphine sulfide ligands [J].

Ahmad, S ;

Isab, AA ;

Perzanowski, HP ;

Hussain, MS ;

Akhtar, MN .

TRANSITION METAL CHEMISTRY, 2002, 27 (02) :177-183

[2] Synthesis of cyano(ergothionine)gold(I) complex and its disproportionation in solution [J].

Ahmad, S ;

Isab, AA .

INORGANIC CHEMISTRY COMMUNICATIONS, 2001, 4 (07) :362-364

[3] Gold(I) complexation with trialkyl/triaryl phosphine selenide ligands [J].

Ahmad, S ;

Akhtar, MN ;

Isab, AA ;

Al-Arfaj, AR ;

Hussain, MS .

JOURNAL OF COORDINATION CHEMISTRY, 2000, 51 (03) :225-234

[4] SYNTHESIS AND CRYSTAL-STRUCTURE OF CYANO(TRIMETHYLPHOSPHINE)GOLD(I) [J].

AHRLAND, S ;

AURIVILLIUS, B ;

DREISCH, K ;

NOREN, B ;

OSKARSSON, A .

ACTA CHEMICA SCANDINAVICA, 1992, 46 (03) :262-265

[5]

Akhtar MN, 1997, POLYHEDRON, V16, P125

[6]

Best S.L., 1996, GOLD BULL, V29, P87, DOI [DOI 10.1007/BF03214741, 10.1007/BF02004707]

[7] Redox and ligand exchange reactions of potential gold(I) and gold(III)-cyanide metabolites under biomimetic conditions [J].

Canumalla, AJ ;

Al-Zamil, N ;

Phillips, M ;

Isab, AA ;

Shaw, CF .

JOURNAL OF INORGANIC BIOCHEMISTRY, 2001, 85 (01) :67-76

[8] Equilibrium binding constants and facile dissociation of novel serum albumin-dicyanoaurate(I) complexes [J].

Canumalla, AJ ;

Schraa, S ;

Isab, AA ;

Shaw, CF ;

Gleichmann, E ;

Dunemann, L ;

Turfeld, M .

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 1998, 3 (01) :9-17

[9] THE ACTIVATION OF GOLD COMPLEXES BY CYANIDE PRODUCED BY POLYMORPHONUCLEAR LEUKOCYTES .2. EVIDENCE FOR THE FORMATION AND BIOLOGICAL-ACTIVITY OF AUROCYANIDE [J].

GRAHAM, GG ;

DALE, MM .

BIOCHEMICAL PHARMACOLOGY, 1990, 39 (11) :1697-1702

[10] The activation of gold complexes by cyanide produced by polymorphonuclear leukocytes - III. The formation of aurocyanide by myeloperoxidase [J].

Graham, GG ;

Kettle, AJ .

BIOCHEMICAL PHARMACOLOGY, 1998, 56 (03) :307-312