The pleomorphic pathology of inherited Parkinson's disease:: Lessons from LRRK2

被引:13
作者
Bonifati, Vincenzo [1 ]
机构
[1] Erasmus MC, Dept Clin Genet, NL-3000 CA Rotterdam, Netherlands
关键词
D O I
10.1007/s11910-996-0013-z
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:355 / 357
页数:3
相关论文
共 20 条
  • [1] Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease
    Berg, D
    Schweitzer, KJ
    Leitner, P
    Zimprich, A
    Lichtner, P
    Belcredi, P
    Brüssel, T
    Schulte, C
    Maass, S
    Nägele, T
    Wszolek, ZK
    Gasser, T
    [J]. BRAIN, 2005, 128 : 3000 - 3011
  • [2] Roc, a Ras/GTPase domain in complex proteins
    Bosgraaf, L
    Van Haastert, PJM
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2003, 1643 (1-3): : 5 - 10
  • [3] G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort
    Bras, JM
    Guerreiro, RJ
    Ribeiro, MH
    Januario, C
    Morgadinho, A
    Oliveira, CR
    Cunha, L
    Hardy, J
    Singleton, A
    [J]. MOVEMENT DISORDERS, 2005, 20 (12) : 1653 - 1655
  • [4] Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease
    Di Fonzo, A
    Tassorelli, C
    De Mari, M
    Chien, HF
    Ferreira, J
    Rohé, CF
    Riboldazzi, G
    Antonini, A
    Albani, G
    Mauro, A
    Marconi, R
    Abbruzzese, G
    Lopiano, L
    Fincati, E
    Guidi, M
    Marini, P
    Stocchi, F
    Onofrj, M
    Toni, V
    Tinazzi, M
    Fabbrini, G
    Lamberti, P
    Vanacore, N
    Meco, G
    Leitner, P
    Uitti, RJ
    Wszolek, ZK
    Gasser, T
    Simons, EJ
    Breedveld, GJ
    Goldwurm, S
    Pezzoli, G
    Sampaio, C
    Barbosa, E
    Martignoni, E
    Oostra, BA
    Bonifati, V
    [J]. EUROPEAN JOURNAL OF HUMAN GENETICS, 2006, 14 (03) : 322 - 331
  • [5] A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1
    Funayama, M
    Hasegawa, K
    Kowa, H
    Saito, M
    Tsuji, S
    Obata, F
    [J]. ANNALS OF NEUROLOGY, 2002, 51 (03) : 296 - 301
  • [6] LRRK2 mutations in Spanish patients with Parkinson disease -: Frequency, clinical features, and incomplete penetrance
    Gaig, C
    Ezquerra, M
    Marti, MJ
    Muñoz, E
    Valldeoriola, F
    Tolosa, E
    [J]. ARCHIVES OF NEUROLOGY, 2006, 63 (03) : 377 - 382
  • [7] Biochemical and pathological characterization of Lrrk2
    Giasson, BI
    Covy, JP
    Bonini, NM
    Hurtig, HI
    Farrer, MJ
    Trojanowski, JQ
    Van Deerlin, VM
    [J]. ANNALS OF NEUROLOGY, 2006, 59 (02) : 315 - 322
  • [8] Common LRRK2 mutation in idiopathic Parkinson's disease
    Gilks, WP
    Abou-Sleiman, PM
    Gandhi, S
    Jain, S
    Singleton, A
    Lees, AJ
    Shaw, K
    Bhatia, KP
    Bonifati, V
    Quinn, NP
    Lynch, J
    Healy, DG
    Holton, JL
    Revesz, T
    Wood, NW
    [J]. LANCET, 2005, 365 (9457) : 415 - 416
  • [9] The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor -: art. no. e65
    Goldwurm, S
    Di Fonzo, A
    Simons, EJ
    Rohé, CF
    Zini, M
    Canesi, M
    Tesei, S
    Zecchinelli, A
    Antonini, A
    Mariani, C
    Meucci, N
    Sacilotto, G
    Sironi, F
    Salani, G
    Ferreira, J
    Chien, HF
    Fabrizio, E
    Vanacore, N
    Dalla Libera, A
    Stocchi, F
    Diroma, C
    Lamberti, P
    Sampaio, C
    Meco, G
    Barbosa, E
    Bertoli-Avella, AM
    Breedveld, GJ
    Oostra, BA
    Pezzoli, G
    Bonifati, V
    [J]. JOURNAL OF MEDICAL GENETICS, 2005, 42 (11) : e65
  • [10] GREGGIO E, 2006, IN PRESS NEUROBIOL D