Future issues in highly conformal radiotherapy for head and neck cancer

被引:21
作者
Feng, Mary [1 ]
Eisbruch, Avraham [1 ]
机构
[1] Univ Michigan, Dept Radiat Oncol, Ann Arbor, MI 48109 USA
关键词
D O I
10.1200/JCO.2006.10.4638
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Improving the conformity of the radiation dose to targets in the head and neck promises reduced toxicity and, in some cases, potentially improved local-regional tumor control. Intensity-modulated radiotherapy (IMRT) is a method that allows highly conformal delivery of radiotherapy. In recent years, its use has spread rapidly in both academic and community radiation oncology facilities. The use of IMRT has raised multiple issues related to target definition, optimal treatment delivery methods, and the need to account for anatomic changes occurring during therapy. Some of these issues are reviewed in this article.
引用
收藏
页码:1009 / 1013
页数:5
相关论文
共 74 条
[1]
Is there a trigger point for adaptive replanning during head & neck IMRT? [J].
Ahamad, A. ;
Dong, L. ;
Zhang, L. ;
Ang, K. ;
O'Daniel, J. ;
Theriot, L. ;
Asper, J. ;
Chambers, M. ;
Palla, S. ;
Garden, A. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 66 (03) :S100-S101
[2]
Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system [J].
Barker, JL ;
Garden, AS ;
Ang, KK ;
O'Daniel, JC ;
Wang, H ;
Court, LE ;
Morrison, WH ;
Rosenthal, DI ;
Chao, KSC ;
Tucker, SL ;
Mohan, R ;
Dong, L .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2004, 59 (04) :960-970
[3]
Non-invasive imaging of alpha-v-beta-3-expression in head-and-neck cancer patients with (18F)Galacto-RGD and positron emission tomography [J].
Beer, A. J. ;
Grosu, A. L. ;
Sarbia, M. ;
Wester, H. J. ;
Haubner, R. ;
Molls, M. ;
Weber, W. A. ;
Schwaiger, M. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 66 (03) :S425-S426
[4]
Beer AJ, 2006, J NUCL MED, V47, P763
[5]
Modulated beam conformal therapy for head and neck tumors [J].
Boyer, AL ;
Geis, P ;
Grant, W ;
Carol, M .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 39 (01) :227-236
[6]
FDG pet studies during treatment:: Prediction of therapy outcome in head and neck squamous cell carcinoma [J].
Brun, E ;
Kjellén, E ;
Tennvall, J ;
Ohlsson, T ;
Sandell, A ;
Perfekt, R ;
Wennerberg, J ;
Strand, SE .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2002, 24 (02) :127-135
[7]
Smart (simultaneous modulated accelerated radiation therapy) boost: A new accelerated fractionation schedule for the treatment of head and neck cancer with intensity modulated radiotherapy [J].
Butler, EB ;
Teh, BS ;
Grant, WH ;
Uhl, BM ;
Kuppersmith, RB ;
Chiu, JK ;
Donovan, DT ;
Woo, SY .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1999, 45 (01) :21-32
[8]
Chao KSC, 2000, INT J CANCER, V90, P92, DOI 10.1002/(SICI)1097-0215(20000420)90:2<92::AID-IJC5>3.0.CO
[9]
2-9
[10]
A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy [J].
Chao, KSC ;
Bosch, WR ;
Mutic, S ;
Lewis, JS ;
Dehdashti, F ;
Mintun, MA ;
Dempsey, JF ;
Perez, CA ;
Purdy, JA ;
Welch, MJ .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2001, 49 (04) :1171-1182