Prostate cancer schemes for androgen escape

被引：60

作者：

Brinkmann, AO

Trapman, J

机构：

[1] Erasmus Univ, Med Ctr Rotterdam, Dept Endocrinol & Reprod, NL-3000 DR Rotterdam, Netherlands

[2] Erasmus Univ, Med Ctr Rotterdam, Dept Pathol, NL-3000 DR Rotterdam, Netherlands

来源：

NATURE MEDICINE | 2000年 / 6卷 / 06期

关键词：

D O I：

10.1038/76194

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A double mutation in the androgen receptor allows prostate cancer cells to become responsive to glucocorticoids. This discovery sheds light on a new pathway by which prostate cancer cells can escape androgen dependence (pages 703–706).

引用

页码：628 / 629

页数：2

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