Education and the incidence of dementia in a large population-based study: The Rotterdam Study

被引：74

作者：

Ott, A

van Rossum, CTM

van Harskamp, F

van de Mheen, H

Hofman, A

Breteler, MMB

机构：

[1] Erasmus Univ, Sch Med, Dept Epidemiol & Biostat, NL-3000 DR Rotterdam, Netherlands

[2] Erasmus Univ, Sch Med, Dept Publ Hlth, NL-3000 DR Rotterdam, Netherlands

[3] Erasmus Univ, Sch Med, Dept Neurol, NL-3000 DR Rotterdam, Netherlands

来源：

NEUROLOGY | 1999年 / 52卷 / 03期

关键词：

D O I：

10.1212/WNL.52.3.663

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We assessed the risk of dementia by educational level in a prospective population-based study. In the Rotterdam Study, 6,827 nondemented participants with known education level were followed for an average of 2.1 years. During this period, 137 new cases of dementia occurred. Low education was associated with higher dementia risk in women but not in men, suggesting that the association is modified by sex. Our data indicate that cross-sectional studies may overrate the association between education and risk of dementia.

引用

收藏

页码：663 / 666

页数：4

相关论文

共 10 条

[1]

Albert M S, 1995, Ann Epidemiol, V5, P76, DOI 10.1016/1047-2797(94)00044-T

[2] LACK OF ASSOCIATION BETWEEN ALZHEIMERS-DISEASE AND EDUCATION, OCCUPATION, MARITAL-STATUS, OR LIVING ARRANGEMENT [J].

BEARD, CM ;

KOKMEN, E ;

OFFORD, KP ;

KURLAND, LT .

NEUROLOGY, 1992, 42 (11) :2063-2068

[3] Increased risk of mortality in Alzheimer's disease patients with higher education? A replication study [J].

Geerlings, MI ;

Deeg, DJH ;

Schmand, B ;

Lindeboom, J ;

Jonker, C .

NEUROLOGY, 1997, 49 (03) :798-802

[4] DETERMINANTS OF DISEASE AND DISABILITY IN THE ELDERLY - THE ROTTERDAM ELDERLY STUDY [J].

HOFMAN, A ;

GROBBEE, DE ;

DEJONG, PTVM ;

VANDENOUWELAND, FA .

EUROPEAN JOURNAL OF EPIDEMIOLOGY, 1991, 7 (04) :403-422

[5] EDUCATION AND THE PREVALENCE OF DEMENTIA AND ALZHEIMERS-DISEASE [J].

KATZMAN, R .

NEUROLOGY, 1993, 43 (01) :13-20

[6] PREVALENCE OF ALZHEIMERS-DISEASE AND VASCULAR DEMENTIA - ASSOCIATION WITH EDUCATION - THE ROTTERDAM STUDY [J].

OTT, A ;

BRETELER, MMB ;

VANHARSKAMP, F ;

CLAUS, JJ ;

VANDERCAMMEN, TJM ;

GROBBEE, DE ;

HOFMAN, A .

BRITISH MEDICAL JOURNAL, 1995, 310 (6985) :970-973

[7]

Ott A, 1998, AM J EPIDEMIOL, V147, P574

[8] Linguistic ability in early life and cognitive function and Alzheimer's disease in late life - Findings from the Nun Study [J].

Snowdon, DA ;

Kemper, SJ ;

Mortimer, JA ;

Greiner, LH ;

Wekstein, DR ;

Markesbery, WR .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 275 (07) :528-532

[9] INCREASED RISK OF MORTALITY IN ALZHEIMERS-DISEASE PATIENTS WITH MORE ADVANCED EDUCATIONAL AND OCCUPATIONAL ATTAINMENT [J].

STERN, Y ;

TANG, MX ;

DENARO, J ;

MAYEUX, R .

ANNALS OF NEUROLOGY, 1995, 37 (05) :590-595

[10] RELATIONSHIP BETWEEN LIFETIME OCCUPATION AND, PARIETAL FLOW - IMPLICATIONS FOR A RESERVE AGAINST ALZHEIMERS-DISEASE PATHOLOGY [J].

STERN, Y ;

ALEXANDER, GE ;

PROHOVNIK, I ;

STRICKS, L ;

LINK, B ;

LENNON, MC ;

MAYEUX, R .

NEUROLOGY, 1995, 45 (01) :55-60