The stages of type 1A diabetes

被引：16

作者：

Babaya, N ^{[1
]}

Nakayama, M ^{[1
]}

Eisenbarth, GS ^{[1
]}

机构：

[1] Univ Colorado, Hlth Sci Ctr, Barbara Davis Ctr Childhood Diabet, Aurora, CO 80010 USA

来源：

AUTOIMMUNE DISEASES AND TREATMENT: ORGAN-SPECIFIC AND SYSTEMIC DISORDERS | 2005年 / 1051卷

关键词：

NOD mouse; prediction; genetic susceptibility; environmental factor; autoantibody; trial; transplantation; review;

D O I：

10.1196/annals.1361.061

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We can now predict the development of type 1 diabetes in man because it is a chronic autoimmune disorder with defined stages of disease. We can also readily prevent the disorder in animal models. A major goal is safe prevention in man, and for this we will almost certainly need a better understanding of pathogenesis, coupled with rigorous clinical trials.

引用

页码：194 / 204

页数：11

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