Assessment of simple movements and progression of Huntington's disease

被引：14

作者：

Andrich, Juergen ^{[1
]}

Saft, Carsten ^{[1
]}

Ostholt, Natalie ^{[1
]}

Mueller, Thomas ^{[1
]}

机构：

[1] Ruhr Univ Bochum, Dept Neurol, St Josef Hosp, D-44791 Bochum, Germany

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2007年 / 78卷 / 04期

关键词：

D O I：

10.1136/jnnp.2006.105338

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Instrumental measurement of simple motion sequences reflects impairment in patients with Huntington's disease (HD). The objectives were to study the progress of symptoms of HD and tapping results in 42 patients with HD, without symptomatic drug treatment over 3 years. Assessment moments were at baseline, and at years 1, 2 and 3. Unified Huntington's Disease Rating Scale (UHDRS) total score and UHDRS arm score significantly increased. Motor test outcomes considerably worsened. Instrumental test results significantly correlated with both UHDRS scores at each assessment. Assessment of simple movement sequences is an additional simple method to follow impairment in patients with HD in addition to clinical rating.

引用

页码：405 / 407

页数：3

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