In vitro effects on bacterial growth of phenoloxidase reaction products

被引：52

作者：

Cerenius, Lage ^{[1
]}

Babu, Ramesh ^{[1
]}

Soderhall, Kenneth ^{[1
]}

Jiravanichpaisal, Pikul ^{[1
]}

机构：

[1] Uppsala Univ, Dept Comparat Physiol, SE-75236 Uppsala, Sweden

来源：

JOURNAL OF INVERTEBRATE PATHOLOGY | 2010年 / 103卷 / 01期

基金：

瑞典研究理事会;

关键词：

Melanin formation; Prophenoloxidase-activating system; Bactericidal; Innate immunity; Crustacean; Agglutination; Hemocyte; INSECT;

D O I：

10.1016/j.jip.2009.09.006

中图分类号：

Q95 [动物学];

学科分类号：

071002 [动物学];

摘要：

An active phenoloxidase preparation from the freshwater crayfish Pacifastacus leniusculus exhibited a strong antibacterial effect in vitro on the bacteria Aeromonas hydrophila, Escherichia coli, Streptococcus pneumoniae whereas a weaker but still significant effect against Bacillus cereus, Pseudomonas aeruginosa and Staphylococcus aureus. In most cases reduction of bacterial growth was stronger when dopamine was used as substrate as compared to L-dopa. The effect on bacteria was abolished if no substrate was available for the phenoloxidase or in the presence of the phenoloxidase inhibitor phenylthiourea. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：21 / 23

页数：3

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