Clarithromycin resistance and eradication of Helicobacter pylori in children

被引:50
作者
Kalach, N
Benhamou, PH
Campeotto, F
Bergeret, M
Dupont, C
Raymond, J
机构
[1] Hop St Vincent de Paul, Dept Microbiol, F-75674 Paris 14, France
[2] Hop St Vincent de Paul, Dept Pediat, Div Gastroenterol, F-75674 Paris 14, France
[3] Univ Catholique Lille, Hop St Antoine, Dept Pediat, F-59000 Lille, France
关键词
D O I
10.1128/AAC.45.7.2134-2135.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Outcome of Helicobacter pylori infection was analyzed in 61 children treated with a triple therapy including clarithromycin. Bacterial eradication was obtained in all children with clarithromycin-susceptible strains but not in children,vith clarithromycin-resistant ones (P = 0.0001). H. pylori antimicrobial susceptibility is mandatory before choosing a treatment, and clarithromycin should be avoided in case of resistance.
引用
收藏
页码:2134 / 2135
页数:2
相关论文
共 14 条
[1]  
[Anonymous], 1999, M100S9 NAT COMM CLIN
[2]  
BELL GD, 1992, ALIMENT PHARM THERAP, V6, P427
[3]   Different penicillin-binding protein profiles in amoxicillin-resistant Helicobacter pylori [J].
Dore, MP ;
Graham, DY ;
Sepulveda, AR .
HELICOBACTER, 1999, 4 (03) :154-161
[4]   Effect of pretreatment antibiotic resistance to metronidazole and clarithromycin on outcome of Helicobacter pylori therapy -: A meta-analytical approach [J].
Dore, MP ;
Leandro, G ;
Realdi, G ;
Sepulveda, AR ;
Graham, DY .
DIGESTIVE DISEASES AND SCIENCES, 2000, 45 (01) :68-76
[5]  
Drumm Brendan, 2000, JPGN, V30, P207, DOI 10.1097/00005176-200002000-00020
[6]   Clarithromycin resistance in Helicobacter pylori infection:: Does it matter? [J].
Fock, KM .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2000, 15 (10) :1089-1092
[7]   Relationship between Helicobacter pylori eradication and reduced duodenal and gastric ulcer recurrence: A review [J].
Hopkins, RJ ;
Girardi, LS ;
Turney, EA .
GASTROENTEROLOGY, 1996, 110 (04) :1244-1252
[8]  
HUANG JQ, 1999, GUT S1, V45, P40
[9]  
KALACH N, 2001, IN PRESS J CLIN MICR
[10]   Antibiotic-resistant H-pylori infection and its treatment [J].
Qureshi, WA ;
Graham, DY .
CURRENT PHARMACEUTICAL DESIGN, 2000, 6 (15) :1537-1544