In vivo evidence that retinal bipolar cells generate spikes modulated by light

被引:50
作者
Dreosti, Elena [1 ]
Esposti, Federico [1 ]
Baden, Tom [1 ]
Lagnado, Leon [1 ]
机构
[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
基金
英国惠康基金;
关键词
EXOCYTOSIS; CHANNELS; CURRENTS; INFLUX;
D O I
10.1038/nn.2841
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Retinal bipolar cells have been assumed to generate purely graded responses to light. To test this idea we imaged the presynaptic calcium transient in live zebrafish. We found that ON, OFF, transient and sustained bipolar cells are all capable of generating fast 'all-or-none' calcium transients modulated by visual stimulation.
引用
收藏
页码:951 / 952
页数:2
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