Asymmetric catalytic aza-Henry reactions leading to 1,2-diamines and 1-,2-diaminocarboxylic acids

被引：193

作者：

Westermann, B ^{[1
]}

机构：

[1] Univ Gesamthsch Paderborn, Fac Nat Sci, D-33095 Paderborn, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 02期

关键词：

asymmetric syntheses; aza-Henry reactions; diamines; Lewis acids; Mannich reactions;

D O I：

10.1002/anie.200390071

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the wake of the aldol and Mannich reactions, textbook examples of asymmetric reactions, comes the aza-Henry reaction (aka nitro-Mannich reaction), which leads to 1,2-diamines or α,β-diaminocarboxylic acids (see scheme, PG= protecting group). Recent developments point to a bright future for this transformation.

引用

页码：151 / 153

页数：3

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