The role of scavenger receptors in pathogen recognition and innate immunity

被引:153
作者
Mukhopadhyay, S [1 ]
Gordon, S [1 ]
机构
[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England
基金
英国医学研究理事会; 英国惠康基金;
关键词
scavenger receptors;
D O I
10.1016/j.imbio.2004.02.004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 [免疫学];
摘要
Scavenger receptors represent a large family of structurally unrelated distinct gene products, expressed by myeloid and selected endothelial cells and able to recognise modified low-density lipoproteins. They also bind and internalise a variety of microbial pathogens, as well as modified or endogenous molecules derived from the host, and contribute to a range of physiological or pathological processes. (C) 2004 Elsevier GmbH. All rights reserved.
引用
收藏
页码:39 / 49
页数:11
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