Direct reductive amination of carbonyl compounds using bis(triphenylphosphine) copper(I) tetrahydroborate

被引：52

作者：

Bhanushali, Mayur J. ^{[1
]}

Nandurkar, Nitin S. ^{[1
]}

Bhor, Malhari D. ^{[1
]}

Bhanage, Bhalchandra M. ^{[1
]}

机构：

[1] Inst Chem Technol, Dept Chem, Bombay 400019, Maharashtra, India

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 07期

关键词：

reductive animation; bis(triphenylphosphine) copper(I) tetrahydroborate; carbonyl compounds; amines;

D O I：

10.1016/j.tetlet.2006.12.037

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A direct reductive amination protocol for a Idehydes/ket ones using bis(triphenylphosphine) copper(I) tetrahyd rob orate as a novel reducing agent in the presence of sulfamic acid has been developed. The reagent chemoselectively reduces the imine moiety and does not affect other reducible functionalities such as chloro, nitro, cyano and methoxy. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：1273 / 1276

页数：4

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