Exploitation of the Ugi 4CC reaction: Preparation of small molecule combinatorial libraries via solid phase

被引：59

作者：

Short, KM ^{[1
]}

Ching, BW ^{[1
]}

Mjalli, AMM ^{[1
]}

机构：

[1] ONTOGEN CORP,CARLSBAD,CA 92009

来源：

TETRAHEDRON | 1997年 / 53卷 / 19期

关键词：

D O I：

10.1016/S0040-4020(97)00223-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The potential of the Ugi 4CC reaction has been explored with regard to the preparation of large combinatorial libraries of small organic molecules of varying structures. These include small-ring lactams, alpha-(dialkylamino)amides, hydantoin 4-imides, 2-thiohydantoin 4-imides and 5-(1'-aminoalkyl)tetraoles. (C) 1997 Published by Elsevier Science Ltd.

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页码：6653 / 6679

页数：27

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