Nonsequence-specific DNA recognition: a structural perspective

被引：124

作者：

Murphy, FV

Churchill, MEA

机构：

[1] Univ Colorado, Hlth Sci Ctr, Dept Pharmacol, Denver, CO 80262 USA

[2] Univ Illinois, Dept Biochem, Urbana, IL 61801 USA

来源：

STRUCTURE WITH FOLDING & DESIGN | 2000年 / 8卷 / 04期

关键词：

D O I：

10.1016/S0969-2126(00)00126-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chromosomal proteins that form essential architectural components of chromatin bind and bend DNA with an intrinsic low degree of sequence preference. Comparisons made between two recently determined structures of high mobility group (HMG) protein-DNA complexes and other nonsequence-specific protein-DNA complexes reveal the structural basis of this important mode of DNA binding.

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页码：R83 / R89

页数：7

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