Interaction of non-alcoholic fatty liver disease with other liver diseases

被引：48

作者：

Clouston, AD

Powell, EE

机构：

[1] Princess Alexandra Hosp, Dept Gastroenterol & Hepatol, Brisbane, Qld 4102, Australia

[2] Univ Queensland, Brisbane, Qld 4067, Australia

[3] Sullivan Nicolaides Pathol, Brisbane, Qld, Australia

来源：

BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY | 2002年 / 16卷 / 05期

关键词：

co-factor; non-alcoholic steatohepatitis; weight reduction; hepatitis C; alcohol; orthotopic liver transplantation;

D O I：

10.1053/bega.2002.0329

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Obesity-related steatosis is an increasingly common histological finding in liver biopsies and may co-exist with other chronic liver diseases. Although non-alcoholic fatty liver disease (NAFLD) without true steatohepatitis is generally a benign condition, when another liver disease is present, steatosis may exacerbate the liver damage. In this review, we discuss the interaction of obesity-related steatosis with chronic hepatitis C, alcoholic liver disease, disorders of hepatic iron storage and drug-induced liver disease. The role of weight reduction in minimizing liver injury in patients with chronic hepatitis C is discussed. Finally, we discuss the problems associated with orthotopic liver transplantation for patients with NAFLD.

引用

页码：767 / 781

页数：15

共 71 条

[1]

Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity [J].