Microvascular angiogenesis and the renin-angiotensin system

被引：39

作者：

Greene, AS ^{[1
]}

Amaral, SL ^{[1
]}

机构：

[1] Med Coll Wisconsin, Dept Physiol, Milwaukee, WI 53226 USA

来源：

CURRENT HYPERTENSION REPORTS | 2002年 / 4卷 / 01期

关键词：

D O I：

10.1007/s11906-002-0054-x

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

The renin-angiotensin system is one of the major regulatory mechanisms essential for maintaining cardiovascular homeostasis. Angiotensin II is a multifunctional hormone that plays a key role in regulating this system. The importance of the renin-angiotensin system in controlling sodium homeostasis and vascular resistance is well established, however in the past decade, much attention has been focused-on the importance of angiotensin II as a regulator of microvessel density, acting through the AT(1) and AT(2) receptors. In this review, we discuss the connections between the renin-angiotensin system and other growth factor pathways known to be involved in pathologic and physiologic angiogenesis and rarefaction.

引用

页码：56 / 62

页数：7

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