Quantitative Detection of Bioassays with a Low-Cost Image-Sensor Array for Integrated Microsystems

被引:23
作者
Vykoukal, Daynene M. [1 ]
Stone, Gregory P. [1 ,2 ]
Gascoyne, Peter R. C. [1 ]
Alt, Eckhard U. [1 ]
Vykoukal, Jody [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Mol Pathol, Houston, TX 77054 USA
[2] InGeneron Inc, Houston, TX 77054 USA
关键词
analytical methods; colorimetry; droplets; luminescence; microfluidics; FLOW-INJECTION ANALYSIS; OF-CARE DIAGNOSTICS; LAB-ON-VALVE; CAENORHABDITIS-ELEGANS; REAL-TIME; MICROFLUIDICS; POINT; CHIP; TECHNOLOGIES; SYSTEM;
D O I
10.1002/anie.200901814
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Portable assay systems require inexpensive detectors that can be integrated with microfluidic sample handling. Now a mass-produced digital-camera sensor has been interfaced with different lab-on-a-chip architectures to image nanoliter reagent droplets and for quantitative photometry of colorimetric and bioluminescence assays (see contact images of the fluid-handling electrode array (right), and colorimetric (top) and bioluminescent samples (bottom)). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:7649 / 7654
页数:6
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