Vectorial nature of redox Bohr effects in bovine heart cytochrome c oxidase

被引：18

作者：

Capitanio, N ^{[1
]}

Capitanio, G ^{[1
]}

DeNitto, E ^{[1
]}

Papa, S ^{[1
]}

机构：

[1] UNIV BARI, INST MED BIOCHEM & CHEM, POLICLIN BARI, I-70124 BARI, ITALY

来源：

FEBS LETTERS | 1997年 / 414卷 / 02期

关键词：

cytochrome c oxidase; redox Bohr effect; liposome; proton pump;

D O I：

10.1016/S0014-5793(97)01043-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The vectorial nature of redox Bohr effects (redox-linked pK shifts) in cytochrome c oxidase from bovine heart incorporated in liposomes has been analyzed. The Bohr effects linked to oxido-reduction of heme alpha and Cu-B display membrane rectorial asymmetry. This provides evidence for involvement of redox Bohr effects in the proton pump of the oxidase. (C) 1997 Federation of European Biochemical Societies.

引用

页码：414 / 418

页数：5

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