Contralateral neglect induced by right posterior parietal rTMS in healthy subjects

被引:194
作者
Fierro, B
Brighina, F
Oliveri, M
Piazza, A
La Bua, V
Buffa, D
Bisiach, E
机构
[1] Univ Palermo, Inst Neuropsychiat, Neurophysiol Unit, I-90129 Palermo, Italy
[2] IRCCS St Lucia, Rome, Italy
[3] Univ Turin, Dept Psychol, Turin, Italy
关键词
extinction; right parietal cortex; rTMS; visuospatial hemineglect;
D O I
10.1097/00001756-200005150-00030
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We applied repetitive transcranial magnetic stimulation (rTMS) in order to induce interference on visuo-spatial perception in 11 healthy subjects. Subjects performed a visuo-spatial task requiring judgements about the symmetry of prebisected lines. Visual stimuli consisted of symmetrically or asymmetrically transected lines, tachystoscopically presented for 50 ms on a computer-monitor. Performance was examined in basal condition and during rTMS trains of 10 stimuli at 25 Hz, delivered through a focal coil over right or left posterior parietal cortex (P5 and P6 sites) and triggered synchronously with visual stimulus. Randomly intermixed sham rTMS trains were employed to control for non-specific effects. Right parietal rTMS induced a significant rightward bias in symmetry judgements as compared with basal and sham rTMS conditions. No differences emerged between other conditions. NeuroReport 11:1519-1521 (C) 2000 Lippincott Williams & Wilkins.
引用
收藏
页码:1519 / 1521
页数:3
相关论文
共 13 条
[1]   SUPPRESSION OF VISUAL-PERCEPTION BY MAGNETIC COIL STIMULATION OF HUMAN OCCIPITAL CORTEX [J].
AMASSIAN, VE ;
CRACCO, RQ ;
MACCABEE, PJ ;
CRACCO, JB ;
RUDELL, A ;
EBERLE, L .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1989, 74 (06) :458-462
[2]   Temporal aspects of visual search studied by transcranial magnetic stimulation [J].
Ashbridge, E ;
Walsh, V ;
Cowey, A .
NEUROPSYCHOLOGIA, 1997, 35 (08) :1121-1131
[3]   PSEUDONEGLECT - EFFECTS OF HEMISPACE ON A TACTILE LINE BISECTION TASK [J].
BOWERS, D ;
HEILMAN, KM .
NEUROPSYCHOLOGIA, 1980, 18 (4-5) :491-498
[4]   Role of the posterior parietal cortex in updating reaching movements to a visual target [J].
Desmurget, M ;
Epstein, CM ;
Turner, RS ;
Prablanc, C ;
Alexander, GE ;
Grafton, ST .
NATURE NEUROSCIENCE, 1999, 2 (06) :563-567
[5]  
LEONE AP, 1999, T R PHIL SOC, V354, P1229
[6]   Visuospatial attention in line bisection: stimulus modulation of pseudoneglect [J].
McCourt, ME ;
Jewell, G .
NEUROPSYCHOLOGIA, 1999, 37 (07) :843-855
[7]   Left frontal transcranial magnetic stimulation reduces contralesional extinction in patients with unilateral right brain damage [J].
Oliveri, M ;
Rossini, PM ;
Traversa, R ;
Cicinelli, P ;
Filippi, MM ;
Pasqualetti, P ;
Tomaiuolo, F ;
Caltagirone, C .
BRAIN, 1999, 122 :1731-1739
[8]   INDUCTION OF VISUAL EXTINCTION BY RAPID-RATE TRANSCRANIAL MAGNETIC STIMULATION OF PARIETAL LOBE [J].
PASCUALLEONE, A ;
GOMEZTORTOSA, E ;
GRAFMAN, J ;
ALWAY, D ;
NICHELLI, P ;
HALLETT, M .
NEUROLOGY, 1994, 44 (03) :494-498
[9]   INDUCTION OF SPEECH ARREST AND COUNTING ERRORS WITH RAPID-RATE TRANSCRANIAL MAGNETIC STIMULATION [J].
PASCUALLEONE, A ;
GATES, JR ;
DHUNA, A .
NEUROLOGY, 1991, 41 (05) :697-702
[10]   Transcranial magnetic stimulation of the human frontal eye field [J].
Thickbroom, GW ;
Stell, R ;
Mastaglia, FL .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 1996, 144 (1-2) :114-118