An Evaluation of Perioperative Pregabalin for Prevention and Attenuation of Postoperative Shoulder Pain After Laparoscopic Cholecystectomy

被引：80

作者：

Chang, Seong-Hwan ^{[2
]}

Lee, Hae-Won ^{[2
]}

Kim, Hae-Kyoung ^{[1
]}

Kim, Seong-Hyop ^{[1
]}

Kim, Duk-Kyung ^{[1
]}

机构：

[1] Konkuk Univ, Sch Med, Dept Anesthesiol & Pain Med, Seoul 143701, South Korea

[2] Konkuk Univ, Sch Med, Dept Surg, Seoul 143701, South Korea

来源：

ANESTHESIA AND ANALGESIA | 2009年 / 109卷 / 04期

关键词：

TRIAL;

D O I：

10.1213/ane.0b013e3181b4874d

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Postlaparoscopic shoulder pain (PLSP) frequently follows laparoscopic surgery. In this placebo-con trolled study, we evaluated the efficacy of two perioperative doses of pregabalin 300 mg 12 h apart for preventing and attenuating PLSP after laparoscopic cholecystectomy. The frequency and severity of PLSP, need for postoperative rescue analgesia, and side effect profiles were assessed for 48 h postoperatively. In both groups, the overall incidence of PLSP did not differ significantly, and the pain score for PLSP, time to first rescue analgesia, and cumulative ketorolac consumption were similar at each timepoint. However, the 2-h postoperative incidence of oversedation was higher with pregabalin. (Anesth Analg 2009;109:1284-6)

引用

页码：1284 / 1286

页数：3

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