Prospective assessment of a nomogram for the initiation of oral anticoagulation therapy for outpatient treatment of venous thromboembolism

被引：9

作者：

Kovacs, MJ

Anderson, DA

Wells, PS

机构：

[1] London Hlth Sci Ctr, Dept Med, London, ON N6A 4G5, Canada

[2] Queen Elizabeth II Hlth Sci Ctr, Halifax, NS, Canada

[3] Ottawa Civic Hosp, Ottawa, ON K1Y 4E9, Canada

来源：

PATHOPHYSIOLOGY OF HAEMOSTASIS AND THROMBOSIS | 2002年 / 32卷 / 03期

关键词：

warfarin; nomogram; venous thromboembolism;

D O I：

10.1159/000065215

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Venous thromboembolism is a common medical problem. Recently, the emphasis has been on a switch to outpatient low molecular weight heparin therapy. Previous warfarin nomograms have been developed only for inpatients. We prospectively assessed a warfarin initiation nomogram in 105 consecutive outpatients; the nomogram requires International Normalized Ratio (INR) testing on only days 3, 5, and 8. Eighty-three percent had a therapeutic INR by day 5 and 98% by day 8. There were no major bleeds and only 6 instances of INR >4.5. This outpatient warfarin nomogram appears to be safe and efficacious in obtaining timely therapeutic levels of warfarin and deserves further study. Copyright (C) 2002 S. Karger AG, Basel.

引用

收藏

页码：131 / 133

页数：3

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