Treatment of heart failure with autologous skeletal myoblasts

被引：5

作者：

Chachques, JC

Cattadori, B

Herreros, J

Prosper, F

Trainini, JC

Blanchard, D

Fabiani, JN

Carpentier, A

机构：

[1] Univ Paris, Pompidou Hosp, Dept Cardiac Surg, F-75015 Paris, France

[2] Univ Paris, Broussais Hosp, Dept Cardiac Surg, F-75015 Paris, France

[3] Univ Navarra, E-31080 Pamplona, Spain

来源：

HERZ | 2002年 / 27卷 / 07期

关键词：

cellular cardiomyoplasty; cellular biology; myoblasts; cell transplantation; myocardial infarction; congestive heart failure;

D O I：

10.1007/s00059-002-2422-3

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Background: The management of patients with heart failure is a daily challenge for cardiologists and cardiac surgeons. Pharmacotherapy, atrio-biventricular resynchronization, myocardial revascularization, valve repair techniques, latissimus dorsi cardiomyoplasty, acorn cardiac support device, heart transplantation and mechanical assist devices do not cover all the needs. The recent progress in cellular and molecular biology allows the development of new therapies for heart failure. Transplantation of Autologous Cells: One of the most in novative consists in the transplantation of autologous ex-vivo expanded cells into the myocardium for heart muscle regeneration. This approach is called "cellular cardiomyoplasty".

引用

页码：570 / 578

页数：9

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