Preparation of [11C] radioligands with high specific radioactivity on a commercial PET tracer synthesizer

被引:18
作者
Matarrese, M
Soloviev, D
Todde, S
Neutro, F
Petta, P
Carpinelli, A
Brüssermann, M
Kienle, MG [1 ]
Fazio, F
机构
[1] Univ Milan, IBFH CNR, Inst H San Raffaele, Milan, Italy
[2] Nucl Interface Gmbh, Munster, Germany
关键词
specific radioactivity; Nuclear Interface PET Tracer; C-11]radioligands; 2-C-11]acetone; C-11]methyl iodides; C-11]methyl triflate;
D O I
10.1016/S0969-8051(02)00353-0
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
High specific radioactivity is required for receptor studies with PET. Hereby we wish to report our experience using Nuclear Inter-face PET Tracer Synthesizer for preparation of Carbon-11 radioligands and module's modifications, which allowed to achieve high specific radioactivity. (C) 2002 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:79 / 83
页数:5
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